WANG, Ching Chung
Professor of Chemistry & Pharmaceutical Chemistry
Education
1958
National Taiwan University, Taipei, Taiwan (B.S.)
1966
University of California, Berkeley, CA (Ph.D.)
1966-1967
Columbia University, New York, NY (Postdoctoral)
1967-1969
Princeton University, Princeton, NJ (Postdoctoral)
Experience
1969-1981
Senior Investigator, Merck Institute for Therapeutic Research, Rahway, NJ.
1980-2008
Member, Editorial Board, Molecular Biochemical Parasitology.
1981-to-date
Professor of Chemistry and Pharmaceutical Chemistry, University of California, San Francisco, CA. 94143-0446.
1984-1986
Instructor, Biology of Parasitism, Marine Biological Laboratory, Woods Hole, MA.
1984-1988
Member, Tropical Medicine and Parasitology Study Section, Nat'l Institutes of Health.
1987
Chairman, Gordon Research Conference on Immunol. & Mol. Aspects of Parasitism.
1988-1992
Member, National Institutes of Health Reviewers Reserve.
1987-1990
Associate Editor, Experimental Parasitology.
1988-1996
Managing Editor, Molecular Biochemical Parasitology.
1989-1991
Chairman, Steering Committee on Chemotherapy of African Trypanosomiasis, WHO.
1989-1995
Board of Directors of ILRAD, Nairobi, Kenya.
1989-1993
Member, Editorial Committee of the Annual Review of Microbiology.
1991-1994
Director, Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
1991-1996
Chairman, Integrated Chemotherapy Steering Committee, WHO, Geneva, CH
1995-2002
Vice Chairman, Department of Pharmaceutical Chemistry, University of California, San Francisco, CA.
1995-2010
Member, Editorial Board, Antimicrobial Agents and Chemotherapy.
1998-2001
Member, Tropical Medicine and Parasitology Study Section, Nat’l Institutes of Health.
2001-2010
Founding Editor-in-Chief, Eukaryotic Cell, American Society for Microbiology
Honors
1983-1988
Burroughs Wellcome Scholar in Molecular Parasitology.
1983
James Law Distinguished Lecturer, Cornell University.
1986
Barclay McGhee Memorial Lecturer, American Society of Tropical Medicine and Hygiene/American Society for Parasitologists Joint Convention.
1989
Elected Fellow, American Association for the Advancement of Science.
1992
Elected Academician, Academia Sinica, Taiwan
1995
S.Y. Chung Visiting Fellow, New Asia Institute, The Chinese University of Hong Kong.
Bruce M. Greene Award Lecturer, The University of Alabama at Birmingham.
Bruce M. Greene Award Lecturer, The University of Alabama at Birmingham.
1999
Lecturer, President’s Forum of National Cheng-Kung University, Tainan, Taiwan
2004
The Society of Chinese Bioscientists in America Presidential Award
Keynote Speaker, 15th Molecular Parasitology Meeting, Woods Hole, MA
Keynote Speaker, 15th Molecular Parasitology Meeting, Woods Hole, MA
2006
Elected Fellow, American Academy of Microbiology
2007
The Presidential Award, National Yang-Ming University, Taipei, Taiwan
2010
Honorary Doctor’s Degree in Science, National Yang-Ming University, Taipei, Taiwan
Peer Reviewed Publications Since 2007
Total Number of Publications: 280
- Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis. JM Carlton, RP Hirt, JC Silva, AL Delcher, M Schatz, Q Zhao, JR Wortman, SL Bidwell, UC Alsmark, S Besteiro, T Sicheritz-Ponten, CJ Noel, JB Dacks, PG Foster, C Simillion, Y Van de Peer, D Miranda-Saavedra, GJ Barton, GD Westrop, S Muller, D Dessi, PL Fiori, Q Ren, I Paulsen, H Zhang, FD Bastida-Corcuera, A Simoes-Barbosa, MT Brown, RD Hayes, M Mukherjee, CY Okumura, R Schneider, AJ Smith, S Vanacova, M Villalvazo, BJ Haas, M Pertea, TV Feldblyum, TR Utterback, CL Shu, K Osoegawa, PJ de Jong, I Hrdy, L Horvathova, Z Zubacova, P Dolezal, SB Malik, JM Logsdon Jr, K Henze, A Gupta, CC Wang, RL Dunne, JA Upcroft, P Upcroft, O White, SL Salzberg, P Tang, CH Chiu, YS Lee, TM Embley, GH Coombs, JC Mottram, J Tachezy, CM Fraser-Liggett and PJ Johnson. Science 315, 207-212 (2007).
- Inhibition and Structure of Trichomonas vaginalis Purine Nucleoside Phosphorylase with Picomolar Transition State Analogues. A Rinaldo-Mathis, C Wing, M Ghanem, H Deng, P Wu, A Gupta, PC Tyler, GB Evans, RH Furneaux, SC Almo, CC Wang and VL Schramm. Biochemistry 46, 659-668 (2007).
- The Multiple Roles of Cyclin E1 in Controlling Cell Cycle Progression and Cellular Morphology of Trypanosoma brucei. S Gourguechon, JM Savich and CC Wang. J. Mol. Biol. 368, 939-950 (2007).
- Touseled-like Kinase in a Microbial eukaryote Regulates Spindle Assembly and S-Phase Progression by Interacting with Aurora Kinase and Chromatin Assembly Factors. Z Li, S Gourguechon and CC Wang. J. Cell Sci. 120, 3883-3894 (2007).
- Centrin 1 Is Required for Organelle Segregation and Cytokinesis in Trypanosoma brucei. A Selvapandiyan, P Kumar, JC Morris, JL Salisbury, CC Wang and HL Nakhasi. Mol. Biol. Cell 18, 3290-3301 (2007).
- Identification of a Bacterial-like HslVU Protease in the Mitochondria of Trypanosoma brucei and Its Role in Mitochondrial DNA Replication. Z. Li, ME Lindsay, SA Motyka, PT Englund and CC Wang. PLoS Pathogens 4, e1000048 (2008).
- Identification of a Novel Chromosomal Passenger Complex and Its Unique Localization during Cytokinesis in Trypanosoma brucei. Z. Li, JH Lee, F Chu, AL Burlingame, A Gunzl and CC Wang. PLoS ONE 3, e2354 (2008).
- Polo-like Kinase Is Expressed in S/G2/M-phase and Associated with FAZ in Both Procyclic and Bloodstream Trypanosoma brucei. T Umeyama and CC Wang. Eukaryotic Cell 7, 1582-1590 (2008).
- KMP-11, a Basal Body and Flagellar Protein, Is Required for Cell Division in Trypanosoma brucei. Z Li and CC Wang. Eukaryotic Cell 7, 1941-1950 (2008).
- The Chromosomal Passenger Complex and a Mitotic Kinesin Interact with the Tousled-like Kinase in Trypanosoma brucei to Regulate Chromosome Segregation and Cytokinesis. Z Li, T Umeyama and CC Wang. PLoS ONE 3, e3814 (2008).
- snoRNA, a Novel Precursor of microRNA in Giardia lamblia. AA Saraiya and CC Wang. PLoS Pathogens 4, e1000224 (2008).
- The Aurora Kinase in Trypanosoma brucei Plays Distinctive Roles in Metaphase-anaphase Transition and Cytokinetic Initiation. Z Li, T. Umeyama and CC Wang. PLoS Pathogens 5, e1000575 (2009).
- CRK9 Contributes to Regulation of Mitosis and Cytokinesis in the Procyclic Form of Trypanosoma brucei. S Gourguechon and CC Wang. BMC Cell Biology 10, 68 (2009).
- Giardiavirus Internal Ribosome Entry Site Has an Apparently Unique Mechanism of Initiating Translation. S Garlapati and CC Wang. PLoS ONE 4, e7435 (2009).
- Polo-like Kinase Guides Cytokinesis in Trypanosoma brucei through an Indirect Means. Zh Li, T Umeyama, Z Li and CC Wang. Eukaryotic Cell 9, 715-726 (2010).
- Rab11 and Actin Cytoskeleton Participate in Giardia lamblia Encystation, Guiding the Specific Vesicles to the Cyst Wall. A Castillo-Romero, G Leon-Avila, CC Wang, AP Rangel, MC Nuez, CG Tovar, JT Ayala-Sumuano, JP Luna-Arias and JM Hernandez. PLoS Neg. Trop. Dis. 4, e697 (2010).
- A La Autoantigen Homologue Is Required for the Internal Ribosome Entry Site Mediated Translation of Giardiavirus. S Garlapati, AA Saraiya and CC Wang. PLoS ONE 6, e18263 (2011).
- Gene regulation in Giardia lamblia involves a putative microRNA derived from a small nucleolar RNA. W Li, AA Saraiya and CC Wang. PLoS Neg.Trop. Dis. 5, e1338 (2011).
- A microRNA derived from an apparent canonical biogenesis pathway regulates variant surface protein gene expression in Giardia lamblia. AA Saraiya, W Li and CC Wang. RNA 17, 2152-2164 (2011).
- The Structural Basis of Localizing Polo-like Kinase to the Flagellum Attachment Zone in Trypanosoma
- brucei. L Sun and CC Wang. PLoS ONE 6, e27303 (2011).
- The Profile of snoRNA-derived microRNAs That Regulate Expression of Variant Surface Proteins in Giardia lamblia. W Li, AA Saraiya and CC Wang. Cell. Microbiol. 14, 1455-1473 (2012).
- Role of Centrins 2 and 3 in Organelle Segregation and Cytokinesis in Trypanosoma brucei. A Selvapandiyan, P Kumar, JL Salisbury, CC Wang and HL Nakhasi. PLoS ONE 7, e45288 (2012).
- Transition of a microRNA from Repressing to Activating Translation Depending on the Extent of Base Pairing with the Target. AA Saraiya, W Li and CC Wang. PLoS ONE 8, e55672 (2013).
- A Minimal Anaphase Promoting Complex/Cyclosome (APC/C) in Trypanosoma brucei. M Bessat, G
- Knudsen, AL Burlingame and CC Wang. PLoS ONE 8, e59258 (2013).
- Experimental Verification of the Identity of Variant-Specific Surface Proteins in Giardia lamblia Trophozoites. W Li, AA Sarayia and CC Wang. mBio 4, e00321-13 (2013).
- The microRNAs in An Ancient Protist Repress the Variant-specific Surface Protein Expression by Targeting the Entire Coding Sequence. AA Saraiya, W Li, J Wu, CH Chang and CC Wang. PLoS Pathogens 10, e10003791 (2014).
